New iron(III) anti-cancer aminobisphenolate/phenanthroline complexes: Enhancing their therapeutic potential using nanoliposomes
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 623, 2022
Cristina P. Matos , Melissa Albino , Joana Lopes , Ana Silveira Viana , Leonor Côrte-Real , Filipa Mendes , Joao Costa Pessca , Ana Isabel Tomaz , Catarina Pinto Reis , M. Manuela Gaspar , Isabel Correia

Unprecedented collateral sensitivity for cisplatin-resistant lung cancer cells presented by new ruthenium organometallic compounds
INORGANIC CHEMISTRY FRONTIERS, 8, 1983-1996 4 2021
Ricardo G. Teixeira , Dimas C. Belisario , Xavier Fontrodona , Isabel Romero , Ana Isabel Tomaz , M. Helena Garcia , Chiara Riganti , Andreia Valente

Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs
INORGANIC CHEMISTRY, 60, 2914-2930 3 2021
Oscar A. Lenis-Rojas , M Paula Robalo , Ana Isabel Tomaz , A.R. Fernandes , Catarina Roma-Rodrigues , Ricardo G. Teixeira , Fernanda Marques , Monica Folgueira , Julian Yanez , Anabel Alba Gonzalez , Martin Salamini-Montemurri , Dawrin Pech-Puch , Digna Vazquez-Garcia , Margarita Lopez Torres , Alberto Fernandez , Jesus J. Fernandez

Experimental data on novel Fe(III)-complexes containing phenanthroline derivatives for their anticancer properties
DATA IN BRIEF, 27, 12 2019
Cristina P. Matos , Zelal Adiguzel , Yasemin Yildizhan , Buse Cevatemre , Tugba Bagci-Onder , Ozge Cevik , Patrique Nunes , Liliana P. Ferreira , Maria Deus Carvalho , Debora L. Campos , Fernando R. Pavan , Joao Costa Pessoa , Maria Helena Garcia , Ana Isabel Tomaz , Isabel Correia , Ceyda Acilan

May iron(III) complexes containing phenanthroline derivatives as ligands be prospective anticancer agents?
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 176, 492-512 8 2019
Cristina P. Matos , Zelal Adiguzel , Yasemin Yildizhan , Buse Cevatemre , Tugba Bagci Onder , Ozge Cevik , Patrique Nunes , Liliana P. Ferreira , Maria Deus Carvalho , Debora L. Campos , Fernando R. Pavan , J.C. Pessoa , Maria Helena Garcia , Ana Isabel Tomaz , Isabel Correia , Ceyda Acilan

New ternary iron(iii) aminobisphenolate hydroxyquinoline complexes as potential therapeutic agents
DALTON TRANSACTIONS, 48, 8702-8716 6 2019
Cristina P. Matos , Yasemin Yildizhan , Zelal Adiguzel , Fernando R. Pavan , Debora L. Campos , J.C. Pessoa , Liliana P. Ferreira , Ana Isabel Tomaz , Isabel Correia , Ceyda Acilan

Interaction with Blood Proteins of a Ruthenium(II) Nitrofuryl Semicarbazone Complex: Effect on the Antitumoral Activity
MOLECULES, 24, 8 2019
Bruno Demoro , Andreia Bento-Oliveira , Fernanda Marques , J.C. Pessoa , Lucia Otero , Dinorah Gambino , R. F. M. de Almeida , Ana Isabel Tomaz

Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 19, 1262-1275 2019
Lurdes Gano , Teresa Pinheiro , Antonio P. Matos , Francisco Tortosa , Tiago F. Jorge , Maria S. Goncalves , Marta Martins , Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Maria H. Garcia , Fernanda M. Marques

Ru-II(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo
INORGANIC CHEMISTRY, 57, 13150-13166 11 2018
Oscar A. Lenis-Rojas , M Paula Robalo , Ana Isabel Tomaz , Andreia Carvalho , A.R. Fernandes , Fernanda M. Marques , Monica Folgueira , Julian Yanez , Digna Vazquez-Garcia , Margarita Lopez Torres , Alberto Fernandez , Jesus J. Fernandez

Studies on the mechanism of action of antitumor bis(aminophenolate) ruthenium(III) complexes
JOURNAL OF INORGANIC BIOCHEMISTRY, 168, 27-37 3 2017
Orsolya Doemoetoer , R. F. M. de Almeida , Leonor Côrte-Real , Cristina P. Matos , Fernanda M. Marques , Antonio Matos , Carla Real , Tamas Kiss , Eve Anna Enyedy , M. Helena Garcia , Ana Isabel Tomaz

In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 17, 126-136 2017
Nuno Mendes , Francisco Tortosa , Andreia Valente , Fernanda M. Marques , Antonio Matos , Tânia S. Morais , Ana Isabel Tomaz , Fatima Gartner , M. Helena Garcia

Ruthenium new drug: paving the way for cancer therapy
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 22, S122 7 2017
Maria Helena Garcia , Andreia Valente , Tânia S. Morais , Ana Isabel Tomaz

On the mechanism of action of new active ruthenium anticancer compounds: a model membrane biophysics approach
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 22, S179 7 2017
Ana Isabel Tomaz , Andreia D. de Sousa , Telma C. Santos , M. Soledade Santos , M. L. Corvo , Cristina P. Matos , M. Helena Garcia , R. F. M. de Almeida

Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds
FUTURE MEDICINAL CHEMISTRY, 8, 527-544 2016
Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Fernanda M. Marques , M. Helena Garcia

Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites
JOURNAL OF INORGANIC BIOCHEMISTRY, 153, 306-314 12 2015
Mariana Fernandez , Esteban Rodriguez Arce , Cynthia Sarniguet , Tânia S. Morais , Ana Isabel Tomaz , Claudio Olea Azar , Roberto Figueroa , J. Diego Maya , Andrea Medeiros , Marcelo Comini , M. Helena Garcia , Lucia Otero , Dinorah Gambino

The key role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: Ranging from non-cytotoxic to highly cytotoxic compounds
JOURNAL OF INORGANIC BIOCHEMISTRY, 150, 148-159 9 2015
Leonor Côrte-Real , M Paula Robalo , Fernanda M. Marques , Guilherme Nogueira , Fernando Avecilla , Tiago J. L. Silva , Filipa C. Santos , Ana Isabel Tomaz , M. Helena Garcia , Andreia Valente

A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites
Journal of Coordination Chemistry, 68, 2923-2937 2015
Esteban Rodrígues Arce , Cynthia Sarniguet , Tânia S. Morais , Marisol Vieites , Ana Isabel Tomaz , Andrea Medeiros , Marcelo Comini , Javier Varela , Hugo Cerecetto , Mercedes Gonzalez , Fernanda Marques , M. Helena Garcia , Lucia Otero , Dinorah Gambino

The effect of phosphate on the nuclease activity of vanadium compounds
JOURNAL OF INORGANIC BIOCHEMISTRY, 147, 165-176 6 2015
Nataliya Butenko , Jose Paulo Pinheiro , Jose Paulo Da Silva , Ana Isabel Tomaz , Isabel Correia , Vera Ribeiro , J.C. Pessoa , Isabel Cavaco

A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites
JOURNAL OF COORDINATION CHEMISTRY, 68, 2923-2937 2015
Esteban Rodriguez Arce , Cynthia Sarniguet , Tania S. Moraes , Marisol Vieites , Ana Isabel Tomaz , Andrea Medeiros , Marcelo A. Comini , Javier Varela , Hugo Cerecetto , Mercedes Gonzalez , Fernanda M. Marques , M. Helena Garcia , Lucia Otero , Dinorah Gambino

Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 19, 787-803 8 2014
Daniel V. Luis , Joana Silva , Ana Isabel Tomaz , R. F. M. de Almeida , Miguel Larguinho , Pedro V. Baptista , L.M.D.R.S. Martins , Telma F. S. Silva , Pedro M. Borralho , Cecilia M. P. Rodrigues , Antonio Sebastiao Rodrigues , Armando J.L. Pombeiro , A.R. Fernandes